The Western lifestyle has lasting effects on metaflammation

Chronic consumption of a Western diet along with sedentary behaviour causes chronic metabolic inflammation (termed metaflammation) and is 'memorized' by innate immune cells through long-lasting metabolic and epigenetic cellular reprogramming. Lifestyle-associated pathologies have reached epidemic proportions and require a better understanding of the causes of metaflammation and ways to translate this to measures that protect the public from unhealthy diets.