Journal
LUNG CANCER
Volume 105, Issue -, Pages 14-16Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.lungcan.2017.01.005
Keywords
Squamous NSCLC; Adenocarcinoma NSCLC; EGFR
Categories
Funding
- National Cancer Institute Midcareer Investigator Award in Patient-Oriented Research [K24CA201543-01]
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Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition. (C) 2017 Elsevier B.V. All rights reserved.
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