Journal
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
Volume 26, Issue 5, Pages 462-478Publisher
OXFORD UNIV PRESS
DOI: 10.1093/jamia/ocy185
Keywords
blockchain; distributed ledger technology; systematic review; PRISMA; health and Medicine
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Funding
- National Institutes of Health [OT3OD025462]
- UCSD STARS Program
- iDASH Summer Internship Program - National Institutes of Health [T15LM11271]
- National Human Genome Research Institute of the National Institutes of Health [K99/R00HG009680]
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Objectives: To introduce healthcare or biomedical blockchain applications and their underlying blockchain platforms, compare popular blockchain platforms using a systematic review method, and provide a reference for selection of a suitable blockchain platform given requirements and technical features that are common in healthcare and biomedical research applications. Target audience: Healthcare or clinical informatics researchers and software engineers who would like to learn about the important technical features of different blockchain platforms to design and implement blockchain-based health informatics applications. Scope: Covered topics include (1) a brief introduction to healthcare or biomedical blockchain applications and the benefits to adopt blockchain; (2) a description of key features of underlying blockchain platforms in healthcare applications; (3) development of a method for systematic review of technology, based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement, to investigate blockchain platforms for healthcare and medicine applications; (4) a review of 21 healthcare-related technical features of 10 popular blockchain platforms; and (5) a discussion of findings and limitations of the review.
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