Journal
CHINESE JOURNAL OF ORGANIC CHEMISTRY
Volume 39, Issue 4, Pages 982-1012Publisher
SCIENCE PRESS
DOI: 10.6023/cjoc201810006
Keywords
rare actinomycetes; activity compounds; source; structure; biotransformation
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Funding
- National Natural Science Foundation of China [21362010, 81560571, 81660582]
- Key Project of Yunnan Local Colleges Applied Basic Research Project [2017FH001-003]
- Innovative Research Team (in Science and Technology) in University of Yunnan Province
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The microbe is an important source of lead compound. It plays an important role in drug development. Many new active compounds were found from actinomycetes, and the number of new compounds from rare actinomycetes showed an upward trend. This paper introduces the new active compounds including 515 new natural products found in rare actinomycetes, from plants, soil, marine sediment, marine animals and so on. The structure type included macrolides, polyketides, anthraquinones, bipyridines, polyene, etc. The biotransformation of natural products by rare actinomycetes was reported from January 2006 to June 2018.
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