Journal
GELS
Volume 5, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/gels5010014
Keywords
amphiphilic peptides; hydrogels; hydroxyapatite; tissue regeneration; bone; teeth; drug release
Categories
Funding
- MINECO
- FEDER [MAT2015-69547-R, MAT201569367-R]
- Generalitat de Catalunya [2017SGR373, 2017SGR359]
- Generalitat de Catalunya
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Amphiphilic peptides can be self-assembled by establishing physical cross-links involving hydrogen bonds and electrostatic interactions with divalent ions. The derived hydrogels have promising properties due to their biocompatibility, reversibility, trigger capability, and tunability. Peptide hydrogels can mimic the extracellular matrix and favor the growth of hydroxyapatite (HAp) as well as its encapsulation. Newly designed materials offer great perspectives for applications in the regeneration of hard tissues such as bones, teeth, and cartilage. Furthermore, development of drug delivery systems based on HAp and peptide self-assembly is attracting attention.
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