4.7 Review

The role of LNK/SH2B3 genetic alterations in myeloproliferative neoplasms and other hematological disorders

Related references

Note: Only part of the references are listed.
Letter Hematology

Germline transmission of LNKE208Q variant in a family with myeloproliferative neoplasms

Giuseppe Gaetano Loscocco et al.

AMERICAN JOURNAL OF HEMATOLOGY (2016)

Review Hematology

LNK mutations and myeloproliferative disorders

Mary Frances McMullin et al.

AMERICAN JOURNAL OF HEMATOLOGY (2016)

Letter Hematology

LNK mutations in familial myeloproliferative neoplasms

Elisa Rumi et al.

BLOOD (2016)

Article Cardiac & Cardiovascular Systems

LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis

Wei Wang et al.

CIRCULATION RESEARCH (2016)

Review Urology & Nephrology

Linking inflammation and hypertension via LNK/SH2B3

Bethany L. Dale et al.

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2016)

Article Medicine, Research & Experimental

LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors

Ying Cheng et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Cardiac & Cardiovascular Systems

SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis

Michael J. Flister et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2015)

Article Multidisciplinary Sciences

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

Fredrick R. Schumacher et al.

NATURE COMMUNICATIONS (2015)

Article Cardiac & Cardiovascular Systems

SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis

Michael J. Flister et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2015)

Review Endocrinology & Metabolism

12q24 locus association with type 1 diabetes: SH2B3 or ATXN2 ?

Georg Auburger et al.

WORLD JOURNAL OF DIABETES (2014)

Article Hematology

Genetic loss of SH2B3 in acute lymphoblastic leukemia

Arianne Perez-Garcia et al.

BLOOD (2013)

Article Medicine, General & Internal

Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms

Thorsten Klampfl et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Review Immunology

The Lnk Adaptor Protein: A Key Regulator of Normal and Pathological Hematopoiesis

Laura Velazquez

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2012)

Article Biochemistry & Molecular Biology

The SH2B1 Adaptor Protein Associates with a Proximal Region of the Erythropoietin Receptor

Mojib Javadi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Medicine, Research & Experimental

14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells

Jing Jiang et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Multidisciplinary Sciences

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang et al.

NATURE (2012)

Article Hematology

Possible new LNK mutations in myeloproliferative neoplasms

Jung-Sook Ha et al.

AMERICAN JOURNAL OF HEMATOLOGY (2011)

Article Hematology

A nonsynonymous LNK polymorphism associated with idiopathic erythrocytosis

Mary Frances McMullin et al.

AMERICAN JOURNAL OF HEMATOLOGY (2011)

Editorial Material Hematology

Determinants of platelet count in humans

Martina E. Daly

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)

Article Genetics & Heredity

Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection

Alexandra Zhernakova et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2010)

Article Medicine, Research & Experimental

Lnk constrains myeloproliferative diseases in mice

Alexey Bersenev et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Medicine, Research & Experimental

Lnk regulates integrin alpha IIb beta 3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

Hitoshi Takizawa et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Letter Medicine, General & Internal

LNK Mutations in JAK2 Mutation-Negative Erythrocytosis.

Terra L. Lasho et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Genetics & Heredity

Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo

M. Kamran Ikram et al.

PLOS GENETICS (2010)

Article Cardiac & Cardiovascular Systems

Pivotal Role of Lnk Adaptor Protein in Endothelial Progenitor Cell Biology for Vascular Regeneration

Sang-Mo Kwon et al.

CIRCULATION RESEARCH (2009)

Article Cell Biology

Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F

Sigal Gery et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2009)

Article Genetics & Heredity

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

Santhi K. Ganesh et al.

NATURE GENETICS (2009)

Article Genetics & Heredity

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

Daniel F. Gudbjartsson et al.

NATURE GENETICS (2009)

Article Genetics & Heredity

Genome-wide association study identifies eight loci associated with blood pressure

Christopher Newton-Cheh et al.

NATURE GENETICS (2009)

Article Genetics & Heredity

Newly identified genetic risk variants for celiac disease related to the immune response

Karen A. Hunt et al.

NATURE GENETICS (2008)

Article Medicine, General & Internal

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

Deborah J. Smyth et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Multidisciplinary Sciences

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

Jun Seita et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state

Jason H. Kurzer et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Kinase activation through dimerization by human SH2-B

M Nishi et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

A phenylalanine zipper mediates APS dimerization

D Dhe-Sirano et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)

Article Immunology

Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

W Tong et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Immunology

Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice

L Velazquez et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2002)