Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 42, Pages 5934-5937Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc02224d
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Funding
- National Natural Science Foundation of China [21602112, 21674048, 21574064]
- 333 Project of Jiangsu Province [BRA2016379]
- Primary Research & Development Plan of Jiangsu Province [BE2016770]
- China Postdoctoral Science Foundation [2017M621792]
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A small- molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H2S with chlorine. The probe demonstrated specific response to H2S with ratiometric photoacoustic signals in the NIR region, which enabled real- time, accurate, high- resolution imaging of endogenous H2S in vivo.
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