Journal
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
Volume 28, Issue 6, Pages 786-794Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jvir.2017.02.014
Keywords
-
Funding
- National High-tech Research Foundation of China (863 project) [2009AA02Z402, 2012AA022701]
- National Basic Research Program of China (973 program) [2013CB733800, 2013733803]
- Jiangsu Provincial Special Program of Medical Science [BL2013029]
- National Scientific and Technical Achievement Translation Foundation [[2012]258]
- National Natural Science Foundation of China [81471762]
Ask authors/readers for more resources
Purpose: To assess feasibility; safety, and preliminary efficacy of an irradiation portal vein stent for portal vein tumor thrombosis (PVTT) hi patients with hepatocellular carcinoma (HCC): Materials and Methods: Between October 2012 and September 2015, 25 Of 40 patients (mean age of 55.5 y) with PVTT caused by HCC were recruited for treatffierit with an irradiation portal vein stent (self-expandable gent loaded with iodine-125 seeds) at a Single hospital. Liver frinction was classified as Child-Pugh class A in 15 patients (60%) and class B in 10 patients (40%). The Eastern Cooperative Oncology Group performance status score was 0 in 3 Patients (12%); 1 in 13 patients (52%), and 2 in 9 patients (36%). Transarterial chemoembolization was performed after stent placement. Outcomes were measured in terms of technical success, complications, stent patency, and overall survival: Results: The technical success, rate was 92.0% (23/25). No complications grade 3 or higher according to Common Terminology Criteria for Adverse Events were observed. Median stent patency period was 8.0 months (range, 0.6-30.0 months). Between 7 and 955 days after stent placement, 65 cycles of transarteriaI chemoembolization were performed with a mean of 2.8 cycles per patient. Median survival was 12.5 months (range, 0.6-35.7 months). Conclusions: Placement of an irradiation portal vein stent appears feasible and safe and may prolong the patency of the portal vein. It is a promising technique for combining recanalization of an occluded portal vein and brachytherapy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available