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Emerging Perspectives on Applications of Porphyrinoids for Photodynamic Therapy and Photoinactivation of Microorganisms

Journal

MACROHETEROCYCLES
Volume 12, Issue 1, Pages 8-16

Publisher

IVANOVO STATE UNIV CHEMICAL TECHNOLOGY
DOI: 10.6060/mhc181220t

Keywords

Porphyrins; phthalocyanines; photosensitizers; photodynamic therapy; photoinactivation of microorganisms; medical imaging

Funding

  1. Spanish MINECO [CTQ2017-85393-P, PCIN-2017-042/EuroNanoMed2017-191]
  2. Juan de la Cierva fellowship

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The use of photosensitizers (PSs) in photodynamic therapy (PDT) and photodynamic inactivation of microorganisms (PDI), as well in other biomedical techniques as medical imaging, represents a challenge for improving given properties that are desired in a biological media, such as water solubility, lack of aggregation and biocompatibiliry, among others. This review shows the most recent and important examples of the conjugation of photosensitizers to different biomolecules to achieve this goal. The manuscript is written in an accessible way in order to give a general vision of the recent advances stimulating at the same time the curiosity of the reader.

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