Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 45, Pages 6421-6424Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc02734c
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Funding
- Deutsche Forschungsgemeinschaft (DFG) [GRK2062]
- MaxSynBio consortium - Federal Ministry of Education and Research of Germany
- Max Planck Society
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We engineered a synthetic temperature regulation toolbox to enable protocells to sense and respond to heat, utilizing RNA thermometers. The thermo-sensitive protocells were generated by encapsulating temperature feedback transcription/ translation machinery in droplets. Based on these temperature-sensing devices, the protocells can be operated with logic AND gates, differentially processing temperature stimuli into biological signals.
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