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Glycan-modified interfaces in biosensing: an electrochemical approach

Journal

CURRENT OPINION IN ELECTROCHEMISTRY
Volume 14, Issue -, Pages 60-65

Publisher

ELSEVIER
DOI: 10.1016/j.coelec.2018.12.011

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Funding

  1. Slovak Scientific Grant Agency VEGA [2/0137/18, 2/0090/16]
  2. Slovak Research and Development Agency APVV [17-0300]
  3. European Research Council [311532]
  4. ERDF [26240120007]
  5. European Research Council (ERC) [311532] Funding Source: European Research Council (ERC)

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Glycans (complex carbohydrates) attached to various interfacial layers represent a simple but functional model of a cellular surface, which is covered densely by glycans. In this review, we discuss interactions of surface-confined glycans with various glycan-binding proteins, viruses, or pathogenic bacteria. Such glycan receptive interfaces can be applied for bio-sensing of these analytes. In this review, we focus on the application of glycan interfaces for label-free electrochemical biosensing.

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