4.1 Article

Nested Polymerase Chain Reaction with Specific Primers for Mucorales in the Serum of Patients with Hematological Malignancies

Journal

JAPANESE JOURNAL OF INFECTIOUS DISEASES
Volume 72, Issue 3, Pages 196-198

Publisher

NATL INST INFECTIOUS DISEASES
DOI: 10.7883/yoken.JJID.2018.379

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Mucormycosis is an opportunistic infection occurring in immunocompromised hosts with hematological malignancies. Mortality due to mucormycosis in patients with hematological malignancies is high. However, the clinical symptoms of mucormycosis are poorly characterized, and diagnosis is difficult due to the lack of specific culture or serological markers or antigens. We present two cases in which nested polymerase chain reaction with specific primers was used in the serum of patients with hematological malignancies.

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