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Bioinspired superwettable micropatterns for biosensing

Journal

CHEMICAL SOCIETY REVIEWS
Volume 48, Issue 12, Pages 3153-3165

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cs00915e

Keywords

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Funding

  1. National Natural Science Foundation of China [21890742, 21804007, 21727815]
  2. Beijing Natural Science Foundation [2184109, 2182036]
  3. Fundamental Research Funds for Central Universities [FRF-TP-17-066A1]
  4. National Postdoctoral Innovative Talents Support Program of China [BX20180036]
  5. Beijing Municipal Science & Technology Commission [Z161100000116037]

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The bioinspired micropatterns exhibit outstanding capacity in controlling and patterning microdroplets, which have offered new functionalities and possibilities towards a wide variety of emerging biological and biomedical applications. By taking the advantages of the microdroplet anchoring ability, enrichment ability, and the accessibility of such bioinspired micropatterns, the selected topic mainly focuses on the important aspects related to (super) wettable surfaces and their emerging sensing applications (DNA, miRNA, proteins, etc.) by combining them with multiple signal output approaches (fluorescence, colorimetric, SERS, electrochemical, etc.). In the end, we also provide a personal perspective on the future development, and address the remaining challenges in the commercialization of (super) wettable micropatterns towards biosensing.

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