Journal
DYES AND PIGMENTS
Volume 115, Issue -, Pages 120-126Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2014.12.014
Keywords
Fluorescence; Bio-imaging; Probe; Rhodamine; Flurens; Fe3+
Funding
- NSF of China [21272184, 21103137, 20972124]
- Shaanxi Provincial Natural Science Fund Project [2012JQ2007]
- Xi'an City Science and Technology Project [CXY1429, CXY1434]
- Northwest University Science Foundation for Postgraduate Students [YZZ13042]
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Two functionalized rhodamine based probes have been rational designed and synthesized. The probes have sufficiently high selectivity and sensitivity for the detection of Fe3+ ion both by fluorescence and ultraviolet spectroscopy with strong ability of anti-interference performance. The detection process has been shown to be reversible and involves the fluoran ring-opening upon complexation with Fe3+. The obvious fluorescence image obtained from confocal laser scanning microscopy of the detection of Fe3+ in living L929 cells demonstrate that the probes could contribute to significant breakthroughs in understanding the critically important functions of Fe3+ in related cells and biological organs. (C) 2014 Elsevier Ltd. All rights reserved.
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