Journal
DYES AND PIGMENTS
Volume 121, Issue -, Pages 1-6Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2015.05.001
Keywords
Uric acid; Fluorescence; BODIPY; Non-enzymatic; PET; Hydrogen bonding
Funding
- CRI project through the National Research Foundation of Korea [2009-0081566]
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The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: similar to 60 mu M, higher: similar to 700 mu M and normal: similar to 120-380 mu M) with 'turn-on' fluorogenic behaviour. (C) 2015 Elsevier Ltd. All rights reserved.
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