Journal
REACTION CHEMISTRY & ENGINEERING
Volume 4, Issue 7, Pages 1179-1188Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9re00069k
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The preparation of hydantoin scaffolds using modern non-conventional activation methods is herein described. Special attention is devoted to the preparation of hydantoin-based Active Pharmaceutical Ingredients (APIs) by mechanochemistry, highlighting its advantages compared to classical solution procedures, opening new perspectives in the sustainable preparation of useful scaffolds for the pharmaceutical industry.
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