Journal
JOURNAL OF THORACIC IMAGING
Volume 33, Issue 2, Pages 71-80Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RTI.0000000000000270
Keywords
T1-mapping; extracellular volume; diffuse myocardial fibrosis; cardiomyopathy; myocardial tissue characterization
Funding
- Astellas
- Bayer
- Bracco
- GE Healthcare
- Guerbet
- Medrad
- Siemens Healthineers
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Myocardial T1-mapping has become feasible over the past decade as emerging technological magnetic resonance imaging advances enable increasingly rapid and reliable acquisition techniques. A variety of T1-mapping sequences are in development, with most allowing for the acquisition of a single-slice T1-map in a single breath-hold. The development of these protocols has spurred investigation into a wide range of potential clinical uses, including the characterization of cardiomyopathies. Although native T1-mapping provides superior tissue characterization, postcontrast T1-mapping is still indispensable for extracellular volume quantification. Ongoing and future studies should investigate the reliability, reproducibility, accuracy, and precision of available techniques and establish disease-specific reference values for T1-mapping-based parameters.
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