Journal
TOMOGRAPHY
Volume 5, Issue 2, Pages 233-238Publisher
GRAPHO PUBLICATIONS
DOI: 10.18383/j.tom.2019.00002
Keywords
CT re-scan; ultrahigh resolution; ultralow dose; contact detector insert; tomosynthesis; hybrid CT
Funding
- Intramural Research Program of NIH, National Heart, Lung, and Blood Institute
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [ZIAHL006220] Funding Source: NIH RePORTER
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Ultrahigh-resolution, low-dose rescans in a region of interest following a general screening computed tomography (CT) scan is motivated by the need to reduce invasive tissue biopsy procedures in cancer screening. We describe a new method to meet the conflicting demands of ultrahigh resolution, high-speed and ultralowdose, and the first proof-of-concept experiment. With improving detector resolution, the limiting factor for the system resolution of whole-body CT scanners shifts to the penumbra of the source focal spot. The penumbra unsharpness is minimized by inserting flat-panel detector(s) that are in direct contact with the body. In the hybrid system, the detector insert and the CT detector acquire data simultaneously, whereby the standard CT images give the position and orientation of the detector insert(s) as needed for tomosynthesis reconstruction. Imaging tests were performed with a compact photon-counting detector insert on resolution targets of both high-and low-contrast as well as a mouse specimen, all inside a body phantom. Detector insert tomosynthesis provided twice the resolution of the CT scanner alone at the same dose concentration. The short 2-cm beam collimation of the tomosynthesis rescan gave an effective dose equivalent to 6% of an average CT scan in the chest or abdomen.
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