Journal
LAB ON A CHIP
Volume 19, Issue 13, Pages 2220-2232Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9lc00149b
Keywords
-
Categories
Funding
- ERC [306385-SofI]
- French state in the frame of the Investments for the future, Programme IdEx Bordeaux [ANR-10-IDEX-03-02]
- Region Aquitaine
- Institut Universitaire de France
Ask authors/readers for more resources
The high-throughput selection of individual droplets is an essential function in droplet-based microfluidics. Fluorescence-activated droplet sorting is achieved using electric fields triggered at rates up to 30 kHz, providing the ultra-high throughput relevant in applications where large libraries of compounds or cells must be analyzed. To achieve such sorting frequencies, electrodes have to create an electric field distribution that generates maximal actuating forces on the droplet while limiting the induced droplet deformation and avoid disintegration. We propose a metric characterizing the performance of an electrode design relative to the theoretical optimum and analyze existing devices using full 3D simulations of the electric fields. By combining parameter optimization with numerical simulation we derive rational design guidelines and propose optimized electrode configurations. When tested experimentally, the optimized design show significantly better performance than the standard designs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available