3.8 Article

DETERMINATION OF PHENOLIC COMPOUNDS IN PRUNUS DOMESTICA FRUITS EXTRACT AND ITS PHARMACOLOGICAL ACTIVITY

Journal

JOURNAL OF IMAB
Volume 25, Issue 2, Pages 2589-2594

Publisher

GOSPODIN ILIEV PEYTCHINSKI, ED & PUB
DOI: 10.5272/jimab.2019252.2589

Keywords

plum; fruits; extract; phenolic compounds; diuretic; hypouricosemic; membrane-stabilizing effect

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Qualitative composition and content of phenolic compounds in the liquid extract obtained from plum fruits have been studied. Five phenolic substances were found, as gallic acid, three hydroxycinnamic acids and rutin. The dominant substance was neochlorogenic acid (2320 +/- 42 mg/kg). Phenolic substances were identified in the extract and their amount determined by HPLC. Diuretic activity as diurnal spontaneous diuresis and forced diuresis, hypouricosemic and the membrane-stabilizing effects of plum liquid extract and its influence on the rheological properties of blood were studied.

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