Journal
DRUG DISCOVERY TODAY
Volume 20, Issue 9, Pages 1074-1086Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2015.04.009
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Funding
- National Key Scientific Research Project [2012CB947600, 2013BAI04B05]
- National Natural Science Foundation of China [81070540, 81320108006, 81370719]
- Jiangsu Province's Key Discipline/Laboratory of Fetal Medicine and Human Assisted Reproduction
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Herbal products have been used as conventional medicines for thousands of years, particularly in Eastern countries. Thousands of clinical and experimental investigations have focused on the effects and mechanisms-of-action of herbal medicine in the treatment of cardiovascular diseases (CVDs). Considering the history of clinical practice and the great potentials of herb medicine and/or its ingredients, a review on this topic would be helpful. This article discusses possible effects of herbal remedies in the prevention and treatment of CVDs. Crucially, we also summarize some underlying pharmacological mechanisms for herb products in cardiovascular regulations, which might provide interesting information for further understanding the effects of herbal medicines, and boost the prospect of new herbal products against CVDs.
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