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octoFLU: Automated Classification for the Evolutionary Origin of Influenza A Virus Gene Sequences Detected in U.S. Swine

Journal

MICROBIOLOGY RESOURCE ANNOUNCEMENTS
Volume 8, Issue 32, Pages -

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/MRA.00673-19

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Funding

  1. USDA-ARS
  2. USDA-APHIS
  3. NIH-National Institute of Allergy and Infectious Diseases (NIAID)
  4. CRIP (Center of Research in Influenza Pathogenesis), an NIAID [HHSN272201400008C]
  5. U.S. Department of Energy (DOE) [DE-AC05-06OR23100]
  6. USDA [DE-AC05-06OR23100]
  7. USDA Agricultural Research Service, ARS project [050000093-001-00-D]
  8. Iowa State University Veterinary Diagnostic Laboratory
  9. Iowa State University Presidential Interdisciplinary Research Initiative Award

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The diversity of the 8 genes of influenza A viruses (IAV) in swine reflects introductions from nonswine hosts and subsequent antigenic drift and shift. Here, we curated a data set and present a pipeline that assigns evolutionary lineage and genetic Glade to query gene segments.

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