4.3 Article Proceedings Paper

Microwave-assisted Synthesis of Thioesters from Aldehydes and Thiols in Water

Journal

JOURNAL OF THE CHINESE CHEMICAL SOCIETY
Volume 65, Issue 1, Pages 24-27

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/jccs.201700045

Keywords

Aldehydes; Thiols; Microwave irradiation; Aqueous medium; Thioesters

Funding

  1. Ministry of Science and Technology, Taiwan [MOST 105-2113-M-005-001, MOST 104-2113-M-037-001-MY2]
  2. National Chung Hsing University
  3. Kaohsiung Medical University

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We describe the synthesis of thioesters via copper- or iron-catalyzed coupling of thiols with aldehydes on application of microwave irradiation. In this protocol, a variety of aliphatic and aromatic aldehydes and thiols were used, and the products were obtained in good to excellent yields.

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