4.6 Article

Ultrasensitive Raman sensing of alkaline phosphatase activity in serum based on an enzyme-catalyzed reaction

Journal

ANALYTICAL METHODS
Volume 11, Issue 28, Pages 3501-3505

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9ay01033e

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Funding

  1. National Natural Science Foundation of China [21873039, 21573087, 21573092]

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A simple and highly sensitive Raman approach for detecting alkaline phosphatase (ALP) is developed on the basis of the conversion of fosfosal to salicylic acid via an ALP-catalyzed reaction. This method can be used for the clinical detection of ALP in serum.

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