4.6 Review

2018 FDA Tides Harvest

Journal

PHARMACEUTICALS
Volume 12, Issue 2, Pages -

Publisher

MDPI
DOI: 10.3390/ph12020052

Keywords

dotatate; drugs; inotersen; Lutathera; oligonucleotides; Onpattro; patisiran; peptides; pharmaceutical market; Tegsedi

Funding

  1. University of KwaZulu-Natal (South Africa)
  2. Spanish Ministry of Economy, Industry and Competitiveness (MINECO) [CTQ2015-67870-P]
  3. Generalitat de Catalunya (Spain) [2017 SGR 1439]
  4. National Research Foundation (NRF) (CSUR) [105892]
  5. National Research Foundation (NRF) (Blue Sky's Research Programme) [110960]

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In 2018, the United States Food and Drug Administration (FDA) approved a total of 59 new drugs, three of them (5%) are TIDES (or also, -tides), two oligonucleotides and one peptide. Herein, the three TIDES approved are analyzed in terms of medical target, mode of action, chemical structure, and economics.

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