4.2 Review

Role of gut microbiota in brain function and stress-related pathology

Journal

BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH
Volume 38, Issue 3, Pages 75-80

Publisher

BMFH PRESS
DOI: 10.12938/bmfh.19-006

Keywords

behavior; gut microbiota; microglia; resilience; short-chain fatty acids; stress response

Funding

  1. Japan Society for the Promotion of Science (JSPS) KAKENHI [JP 16H05278]
  2. KAKENHI [JP 16K15413, 16H06404]

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Gut microbiota are responsible for a variety of metabolic activities including food digestion and production of biologically active substances. Moreover, several recent works, including our own, have also shown that gut microbiota play an important role not only in the development of brain function but also in the pathology of stress-related diseases and neurodevelopmental disorders. In this review, we focus on the interaction between gut microbes and the brain-gut axis and introduce some basic concepts and recent developments in this area of research.

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