Stereodivergence in Asymmetric Catalysis

This Perspective presents an overview of catalytic enantioselective transformations that allow convenient access to all stereoisomers of a given product with multiple stereogenic centers. Particular focus is placed on discussion of the concept of stereodivergent dual catalysis and its application in target-oriented synthesis. The potential of this concept in the development of new transformations as well as implications for achieving stereochemical diversity in library design and diversity oriented synthesis are also discussed.