Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 139, Issue 50, Pages 18124-18137Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.7b08326
Keywords
-
Categories
Funding
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Canada Foundation for Innovation (CFI)
- Ontario Government
- Queen's University
- Grants-in-Aid for Scientific Research [16K13962, 17H03030, 26288023] Funding Source: KAKEN
Ask authors/readers for more resources
The Suzuki-Miyaura cross-coupling reaction has emerged as one of the most powerful methods for the construction of carbon-carbon bonds. Though most widely utilized for the synthesis of sp(2)-sp(2) linkages, the use of this reaction to form stereochemistry-bearing sp(2)-sp(3) bonds has received widespread attention over the past decade. This Perspective highlights approaches to the synthesis of enantioenriched molecules via the Suzuki-Miyaura reaction. Particular focus is placed on the use of enantiomerically enriched organoboron compounds as coupling partners in stereospecific processes, as well as the development of enantioconvergent and group-selective reactions. In addition, progress in the development of chemoselective, iterative cross-coupling methods will be discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available