Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 139, Issue 40, Pages 13969-13972Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.7b05942
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Funding
- Novartis-MIT Center for Continuous Manufacturing
- Korean Government
- Undergraduate Research Opportunities Program (MIT UROP)
- NSF [CHE-0234877]
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The direct beta-selective hydrocarboxylation of styrenes under atmospheric pressure of CO2 has been developed using photoredox catalysis in continuous flow. The scope of this methodology was demonstrated with a range of functionalized terminal styrenes, as well as alpha-substituted and beta-substituted styrenes.
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