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Polymeric Biomaterials for Management of Pathological Scarring

Journal

ACS APPLIED POLYMER MATERIALS
Volume 1, Issue 4, Pages 612-624

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsapm.8b00203

Keywords

wound healing; pathological scarring; skin; polymer; biomaterials

Funding

  1. Singapore A*STAR Biomedical Research Council
  2. MOE Tier 1 grant [RG131/15]

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Polymeric biomaterials play a significant role in wound care. This article reviews the latest advances in polymeric biomaterials for the care of wound pathologies (i.e., chronic wounds and abnormal scarring). After discussing the development of three categories of polymers (i.e., biodegradable, stimuli-responsive, and bioinspired polymers), we focus on the prevention and treatment of abnormal scarring using polymeric biomaterials. Specific attention is paid to their roles in scar prevention, early detection of abnormal scarring, and antiscarring drug identification.

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