Journal
IEEE ACCESS
Volume 7, Issue -, Pages 92615-92629Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/ACCESS.2019.2927433
Keywords
Brain tumor segmentation; convolutional neural network; multi-cascaded convolutional neural network; conditional random field; multi-modality
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Funding
- National Natural Science Foundation of China [61802328, 61771415]
- Natural Science Foundation of Hunan Province in China [2019JJ50606]
- Cernet Innovation Project [NGII20170702]
- Scientific Research Fund of Hunan Provincial Education Department of China [17A211]
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Accurate segmentation of brain tumor is an indispensable component for cancer diagnosis and treatment. In this paper, we propose a novel brain tumor segmentation method based on multi-cascaded convolutional neural network (MCCNN) and fully connected conditional random fields (CRFs). The segmentation process mainly includes the following two steps. First, we design a multi-cascaded network architecture by combining the intermediate results of several connected components to take the local dependencies of labels into account and make use of multi-scale features for the coarse segmentation. Second, we apply CRFs to consider the spatial contextual information and eliminate some spurious outputs for the fine segmentation. In addition, we use image patches obtained from axial, coronal, and sagittal views to respectively train three segmentation models, and then combine them to obtain the final segmentation result. The validity of the proposed method is evaluated on three publicly available databases. The experimental results show that our method achieves competitive performance compared with the state-of-the-art approaches.
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