Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 76, Issue 3, Pages S100-S109Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2016.09.038
Keywords
cyclobutane pyrimidine dimer; DNA photodamage; photoaging; photoimmunosuppression; pyrimidine(6-4)pyrimidone; skin cancer; sunscreen; ultraviolet radiation
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Funding
- Pierre Fabre Dermo-Cosmetique
- BASF
- Walgreens Boots Alliance
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The efficacy of sunscreens can be measured by different methods, involving in vitro, ex vivo, or in vivo techniques. There is a need for a worldwide standardization of these methods to avoid misunderstanding and confusion among sunscreen users. The clinical benefits of sunscreens have been demonstrated in randomized controlled trials that established the role of sunscreens in the prevention of actinic keratoses, squamous cell carcinomas, nevi, and melanomas. Sunscreens also prevent photoimmuno-suppression and signs of photoaging. Continued efforts in public education on the proper application of sunscreens and the practice of photoprotection in general are needed.
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