4.6 Review

Psoriasis and comorbid diseases Implications for management

Journal

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 76, Issue 3, Pages 393-403

Publisher

MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2016.07.065

Keywords

cardiovascular disease; chronic kidney disease; comorbidities; Crohn's disease; depression; infection; lymphoma; metabolic syndrome; nonalcoholic fatty liver disease; psoriasis; psoriatic arthritis; screening; vaccination

Categories

Funding

  1. National Institute of Arthritis and Musculoskeletal and Skin Diseases [K24AR064310, T32AR00746532, K23AR063764, K23AR068433]
  2. Dermatology Foundation Career Development Award
  3. Intramural Research Program at the National Institutes of Health [ZIAHL006193-02]
  4. National Institute for Health Research Clinician Scientist Fellowship [NIHR/CS/010/014]
  5. Pfizer Inc
  6. AbbVie
  7. Celgene
  8. Amgen
  9. Eli Lilly
  10. Janssen
  11. Novartis Corp
  12. Regeneron
  13. National Institute for Health Research [NIHR/CS/010/014] Funding Source: researchfish

Ask authors/readers for more resources

As summarized in the first article in this continuing medical education series, the currently available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic disease. Emerging data also suggest associations between psoriasis and other comorbidities beyond psoriatic arthritis, including chronic kidney disease, inflammatory bowel disease, hepatic disease, certain malignancies, infections, and mood disorders. Recognizing the comorbid disease burden of psoriasis is essential for ensuring comprehensive care of patients with psoriasis. The clinical implications of the comorbid diseases that are associated with psoriasis and recommendations for clinical management are reviewed in this article.

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