The prevalence of osteoporosis among Iranian postmenopausal women with type 2 diabetes: A systematic review and meta-analysis

Osteoporosis is the most common metabolic bone disorder that is common in postmenopausal women with type 2 diabetes. Different studies have reported different prevalence of osteoporosis. This systematic review and meta-analysis was conducted to estimate the pooled prevalence of osteoporosis in Iranian postmenopausal women with type 2 diabetes. Search for eligible articles was performed using the keywords of osteoporosis, osteopenia, bone mineral density, OP, bone loss, Post menopaus*, diabetes, hyperglycemia, and Iran, and their possible combinations in the following databases: Scientific Information Database (SID), MagIran, PubMed, Scopus, and Web of Science. Heterogeneity between studies was examined with I-2. The data were analyzed using the meta-analysis method and random effects model with Stata version 11.0. The analysis of 4 papers with a sample size of 562 showed that the prevalence of osteoporosis in the lumbar spine and femoral neck of the Iranian post-menopausal women with type II diabetes was 25.26% (95% CI: 7.22-30.30) and 17.45% (95% CI: 0.25-34.65), respectively. Also, the prevalence of osteopenia in the lumbar spine and femoral neck of these patients was 45.23% (95% CI: 40.66-49.79) and 44.53% (95% CI: 36.60-52.47), respectively. There was no relationship between the prevalence of osteoporosis and osteopenia with sample size, year of publication, age and body mass index. Osteoporosis and osteopenia are prevalent in women, so healthy lifestyle education for these postmenopausal women are necessary to reduce the prevalence of these problems. (C) 2019 Diabetes India. Published by Elsevier Ltd. All rights reserved.