Journal
CLINICAL AND EXPERIMENTAL VACCINE RESEARCH
Volume 8, Issue 2, Pages 89-93Publisher
KOREAN VACCINE SOC
DOI: 10.7774/cevr.2019.8.2.89
Keywords
Vaccines; Immune cell dynamics; Non-invasive molecular imaging
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Funding
- Korea Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea [HI15C2971]
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In order to develop a successful vaccine against deadly diseases with a wide range of antigenic diversity, an in-depth knowledge of the molecules and signaling mechanisms between the vaccine candidates and immune cells is required. Therefore, monitoring vaccine components, such as antigen or adjuvants, and immune cell dynamics at the vaccination site or draining lymph nodes can provide important information to understand more about the vaccine response. This review briefly introduces and describes various non-invasive molecular imaging methods for visualizing immune cell dynamics after vaccination.
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