Journal
JOURNAL OF TISSUE ENGINEERING
Volume 10, Issue -, Pages -Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/2041731419877528
Keywords
Therapeutics; nanoparticles; topography; delivery efficiency
Categories
Funding
- Dankook University (Priority Institute Support Program in 2019), Republic of Korea
- National Research Foundation, Republic of Korea [2018K1A4A3A01064257, 2017R1C1B1011387, 2018R1A2B3003446]
- National Research Foundation of Korea [2017R1C1B1011387] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
Nanoparticle-based therapeutics delivery holds great promise for the treatment of intractable diseases. The high loading of drug molecules and their precise delivery to target sites are needed to gain optimal therapeutic functions of the nanoparticle delivery system. In this communication, we highlight, among other properties of nanoparticles (e.g. size, shape, surface chemistry, and degradation), the nanoscale topography, which has recently been shown to be an important parameter, ultimately determining drug loading, cell penetration, and body clearance. This nanotopographical aspect is considered to offer a new effective strategy to the development of nanoparticles for drug and gene delivery with enhanced therapeutic outcome.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available