Journal
COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XIV
Volume 10892, Issue -, Pages -Publisher
SPIE-INT SOC OPTICAL ENGINEERING
DOI: 10.1117/12.2506870
Keywords
terahertz time-domain spectroscopy; iron oxide; magnetite; silica; nanoparticles; polyethylene; glycose; pellets
Funding
- RFBR / RFBR-CNRS [18-51-16002, 17-00-00275, 17-00-00272, 17-00-00184]
- Government of the Russian Federation [08-08, N0035-2014-0206]
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Drag-laden magnetic nanoparticles can deliver drugs to a zone of ischemic damage for various purposes of clinical medicine. THz spectroscopy of nanoparticles with adsorbed organic and biological molecules could enable estimation of drug delivery efficiency of the nanoparticles sample and curative effect of delivering chemical substance. The first task of this work was to simulate the contribution of nanoparticles and the shell of organic molecules (glycose) to the dielectric properties of the pressed pellets, consisting of the polyethylene and nanoparticles. The second task of this paper was to study experimentally the possibility of using terahertz radiation for spectral diagnosis of NPs based on iron oxide in a biologically inert shell of silicon dioxide drug-laden with a glycose.
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