Journal
SN APPLIED SCIENCES
Volume 1, Issue 8, Pages -Publisher
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/s42452-019-0963-9
Keywords
Biomineralization; Cuprous oxide; Bovine serum albumin; Hierarchical nanocomposite particles; Antibacterial
Categories
Funding
- United Innovation Program of Shanghai Commercial Aircraft Engine Fund [AR909]
- Municipal Bureau of Quality and Technical Supervision Project of Shanghai (2018)
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A facile method to prepare cuprous oxide/bovine serum albumin (Cu2O/BSA) hierarchical nanocomposite particles (NCPs) through imitating biomineralization is presented. BSA acted as the structure-directing agents, guiding the nucleation, growth and assembly of Cu(OH)(2) at binding sites to construct the hierarchical structure and then Cu2O/BSA NCPs were achieved. The synthesized nanocomposite with hierarchical structure exhibited excellent antibacterial performance. The products obtained were characterized with XRD, TEM, FTIR, EDX and XPS to investigate the formation mechanism of Cu2O/BSA hierarchical structure. Cu2O/BSA NCPs with size of 20-50 nm built up by several 6-7 nm Cu2O nanocrystals with BSA showed better antibacterial performance in the comparative experiments, which was attributed to the special structure and good biocompatibility of the Cu2O/BSA NCPs. And the possible mechanism was presented to explain the excellent antibacterial properties of Cu2O/BSA NCPs.
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