Journal
QUIMICA NOVA
Volume 42, Issue 7, Pages 768-783Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.21577/0100-4042.20170381
Keywords
immobilization of enzymes; enzymatic properties; biocatalysts; free enzymes; methods of enzyme immobilization
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Funding
- Brazilian Agencies for Scientific and Technological Development
- Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico FUNCAP [BP3-0139-00005.01.00/18]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico CNPq [422942/2016-2]
- Coordenacao de Aperfeicoamento de Ensino Superior (CAPES)
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The enzymatic processes are increasingly highlights, especially in the synthesis of chemical products with high added value. The enzyme immobilization can improve industrial biocatalytic processes. The immobilization of enzymes provides the production of efficient, stable biocatalysts, possibility of reuse and easy purification of the products, when compared to the free enzymes. There is a growing research for more efficient methods of enzyme immobilization. In this context, the choice of support and immobilization strategy can significantly improve the final enzymatic properties. In this review paper, we aimed to discuss the versatility of biocatalysts immobilized enzymes design, focusing on the opportunities and disadvantages for each method presented. They discussed the recent development of enzyme immobilization methods and applications relating the final properties of the produced biocatalysts with the desired goals.
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