A Sensitive and Selective Non-Enzymatic Glucose Sensor based on AuNPs/CuO NWs-MoS2 Modified Electrode

In recent years, copper-based nanomaterials have been widely used in the study of glucose sensors because of its high sensitivity. In this work, a sensitive and selective electrochemical enzyme-free glucose sensor was successfully constructed using a composite of copper oxide nanowires (CuO NWs), molybdenum disulfide (MoS2) and gold nanoparticle (AuNPs). This composite was systematically characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The sensor performance and interface property of the Au electrode modified by NF/AuNPs/CuO-MoS2 were measured by cyclic voltammetry (CV) and chronoamperometric measurements(i-t). Under optimal condition, the proposed sensor shows sensitivity value of 872.71 mu A cm(-2) mM(-1) for glucose, with detection range from 0.5 mu M to 5.67 m. and detection limit of 0.5 mu M. The study also confirms satisfactory selectivity, reproducibility, and stability of the constructed sensor. This NF/AuNPs/CuO NWs-MoS2 sensor performance toward normal human serum spikedwith glucose is determinedwith RSD less than 4.71%, indicating superior potential for the practical quantitative analysis of glucose in serum samples. (C) 2019 The Electrochemical Society.