Journal
JOURNAL OF SEPARATION SCIENCE
Volume 41, Issue 1, Pages 6-19Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.201700201
Keywords
capillary electrophoresis; high-performance liquid chromatography; pentacyclic triterpenoids; quantitative analysis
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Funding
- National Natural Science Foundation of China [81303233]
- Shanghai Committee of Science and Technology [13401900300]
- Budget Program of Shanghai University of Traditional Chinese Medicine [2016YSN22]
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Triterpenes are a major class of chemical compounds found in natural plants and can be categorized into acyclic triterpenoids, monocyclic triterpenoids, tricyclic triterpenoids, tetracyclic triterpenoids, and pentacyclic triterpenoids. Among them, pentacyclic triterpenoids have gained more extensive attention due to their biological activities, including anti-inflammation, antibacterial, antioxidation, antitumor, anti-HIV, hepatoprotection, and immunological adjuvant properties. In this review, we summarize the extraction and analytical methods for pentacyclic triterpenoids, where more than 56 triterpenes from 49 kinds of plants were involved. The analysis methods include gas chromatography, liquid chromatography, capillary electrophoresis, thin-layer chromatography, supercritical fluid chromatography, NMR spectroscopy, and X-ray spectroscopy. This review provides valuable reference for the determination of pentacyclic triterpenoids in medicinal plants.
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