Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 71, Pages 10543-10546Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc04676c
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Funding
- Chemistry Department of the University of Basel
- Swiss National Science Foundation [200021_130263]
- Swiss National Science Foundation (SNF) [200021_130263] Funding Source: Swiss National Science Foundation (SNF)
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Herein we report a DOTA-based lanthanide chelating tag (LCT) with rigidified backbone and a reduction-stable linker. The newly developed tag induces strong pseudocontact shifts suitable for paramagnetic protein nuclear magnetic resonance spectroscopy and the obtained anisotropic susceptibility parameters are in the range of the best performing LCTs.
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