Journal
DISEASE MARKERS
Volume 2015, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2015/864370
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Funding
- Medical Research Council [G1100196] Funding Source: Medline
- Medical Research Council [G1100196] Funding Source: researchfish
- National Institute for Health Research [ACF-2014-09-005] Funding Source: researchfish
- MRC [G1100196] Funding Source: UKRI
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First described in relation to musculoskeletal disease, there is accumulating data to suggest that vitamin D may play an important role in cardiovascular disease (CVD). In this review we aim to provide an overview of the role of vitamin D status as both a marker of and potentially causative agent of hypertension, coronary artery disease, heart failure, atrial fibrillation, stroke, and peripheral vascular disease. The role of vitamin D levels as a disease marker for all-cause mortality is also discussed. We review the current knowledge gathered from experimental studies, observational studies, randomised controlled trials, and subsequent systematic reviews in order to suggest the optimal vitamin D level for CVD protection.
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