4.7 Article

Phosphorylation dependent α-synuclein degradation monitored by in-cell NMR

Journal

CHEMICAL COMMUNICATIONS
Volume 55, Issue 75, Pages 11215-11218

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc05662a

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Funding

  1. Ministry of Science and Technology of China [2017YFA0505400]
  2. National Natural Sciences Foundation of China [21221064, 21203243, 21673284]
  3. K. C. Wong Education Foundation

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Here we report the dephosphorylation and proteolysis of phosphorylated alpha-synuclein, a Parkinson's disease-related protein, in living cells in a time resolved manner using in-cell NMR.

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