Journal
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Volume 60, Issue 13, Pages 4178-4186Publisher
ASSOC RESEARCH VISION OPHTHALMOLOGY INC
DOI: 10.1167/iovs.19-27289
Keywords
emmetropia; refractive errors; ocular growth; ocular biometry; crystalline lens
Categories
Funding
- University of South-Eastern Norway
Ask authors/readers for more resources
PURPOSE. To examine, in Norwegian adolescents, to what degree emmetropia and low hyperopia were maintained from 16 to 18 years of age, and if this was the case, whether it was associated with continued coordinated ocular growth. METHODS. Cycloplegic autorefraction and ocular biometry, including crystalline lens thickness, were measured in 93 Norwegian adolescents (mean age: 16.7 +/- 0.3 years; 63.4% females) and repeated after 2 years. Crystalline lens power was determined by ray tracing over a 1-mm pupil, based on the Gullstrand-Emsley model. Serum vitamin D-3 concentration was measured at follow-up. RESULTS. Emmetropia and low hyperopia (-0.50 diopters [D] < spherical equivalent refractive error [SER] < +2.00 D) were present in 91.4% at baseline and 89.2% at follow-up. The emmetropes and low hyperopes who maintained their refractive error exhibited continued ocular axial growth (+0.059 +/- 0.070 mm) together with a decrease in crystalline lens power (-0.064 +/- 0.291 D) and a deepening of the anterior chamber (+0.028 +/- 0.040 mm). Thinning of the crystalline lens was found in 24%. Overall, the negative change in SER was larger in those with the most negative SER at baseline (R-2 = 0.178, P < 0.001), and was associated with increases in vitreous chamber depth and in crystalline lens power (R-2 = 0.752, P < 0.001), when adjusted for sex. There was no difference in vitamin D-3 level between those who exhibited negative versus positive changes in refractive error. CONCLUSIONS. The results show that emmetropic and low hyperopic eyes were still growing in late adolescence, with refractive errors being maintained through a coordinated decrease in crystalline lens power.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available