4.7 Article

Sensitive and sustained imaging of intracellular microRNA in living cells by a high biocompatible liposomal vehicle introduced isothermal symmetric exponential amplification reaction

Journal

CHEMICAL COMMUNICATIONS
Volume 55, Issue 75, Pages 11251-11254

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc05583e

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Funding

  1. National Natural Science Foundations of China [21775169]
  2. Scientific Technology Project of Guangdong Province [2016B010108007, 2017B020221001]
  3. Scientific Technology Project of Guangzhou City [201604020145]

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A high biocompatible liposomal vehicle was used to deliver enzymes and oligonucleotide substances of the isothermal symmetric exponential amplification reaction into living cells, allowing sensitive and sustained imaging of microRNA in living cells for more than 24 h without apoptosis.

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