4.7 Article

Visible light photocatalytic asymmetric synthesis of pyrrolo[1,2-a]indoles via intermolecular [3+2] cycloaddition

Journal

CHEMICAL COMMUNICATIONS
Volume 55, Issue 75, Pages 11303-11306

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc05838a

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Funding

  1. Spanish Government [RTI2018-095038-B-I00]
  2. European Structural Funds [S2018/NMT-4367]
  3. CAM [2016-T2/IND-1660]

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The intermolecular diastereoselective and enantioselective synthesis of pyrrolo[1,2-a]indoles is developed through a [3+2] cycloaddition between silyl-indole derivatives and alpha,beta-unsaturated N-acyl oxazolidinones by merging photocatalysis and Lewis acid catalysis.

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