Journal
JOURNAL OF PEDIATRICS
Volume 187, Issue -, Pages 318-+Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2017.05.015
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Funding
- Novartis
- National Institute of Neurological Disorders and Stroke of the NIH [U01-NS082320, U54-NS092090, P20-NS080199]
- Tuberous Sclerosis Alliance
- Van Andel Research Institute
- Upsher-Smith Pharmaceuticals
- German Tuberous Sclerosis Foundation
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Renal cysts occur in approximately 50% of patients with tuberous sclerosis complex, but their clinical significance and response to treatment are unknown. Abdominal imaging of 15 patients with tuberous sclerosis complex-associated renal cystic disease who had received mammalian target of rapamycin inhibitor therapy for other tuberous sclerosis complex-related indications was evaluated. Reductions in cyst number, sum diameter, and volume were observed.
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