Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 83, Pages 12547-12550Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc05998a
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Funding
- National Natural Science Foundation of China [21525105, 21778079]
- 973 Program [2015CB856301]
- Ministry of Education of China [IRT-17R111]
- Pearl River S&T Nova Program of Guangzhou [201806010136]
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A mitochondria-targeting hetero-binuclear Ir(iii)-Ru(ii) complex was developed as a photoactivated chemotherapy (PACT) and photodynamic therapy (PDT) bifunctional agent to achieve a synergistic effective therapeutic outcome for the therapy of cisplatin-resistant tumour cells.
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