Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 82, Issue 17, Pages 9198-9203Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01429
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21002076, 21441007]
- Key Projects of Hubei Provincial Department of Education [D20151502]
- Graduate Innovative Fund of Wuhan Institute of Technology [CX2016168]
Ask authors/readers for more resources
A copper-catalyzed three-component reaction of methyl ketones, organic azides, and various one-carbon (C1) donors was developed that provides 4-aryl-1,2,3-triazoles in moderate to good yields. While DMF, DMA, TMEDA, or DMSO can serve as the Cl donor, best yields were obtained using DMF. The transformation is proposed to proceed via an oxidative C-H/C-H cross-dehydrogenative coupling followed by an oxidative 1,3-dipolar cycloaddition.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
